If you plan to use animals for scientific purposes, you must complete an animal use protocol and submit it to an animal care committee for approval prior to commencement of the study. The animal use protocol outlines how the Three Rs will be implemented in the proposed animal-based procedures. To find the most up-to-date information on the Three Rs, investigators typically conduct a structured information search.
To assist investigators with this search, the CCAC has produced the Three Rs Search Guide. This guide is a step-by-step search strategy which provides detailed instructions on how to conduct a Three Rs information search.
We would like to know whether this tool is useful for Canadian investigators and would be grateful if you could send us your feedback at ThreeRs@ccac.ca.

http://3rs.ccac.ca/en/searches-and-animal-index/guide/